Hodos NETWORKS & TRACTS

Lesson text is an educational draft awaiting anatomical review.

Regional anatomy · 10 relationships · 20 minutes · Neurosurgical residents

Central region & descending motor pathways

Orient the central region, follow the descending corridor and distinguish cortical, capsular and cerebellar contributions to movement.

Goals

Start this lesson in the atlas

Relationships

Relationship 1 of 10 · atlas

Find the two banks of the central sulcus

Orient

Start with a relationship: the precentral gyrus lies anterior to the central sulcus; the postcentral gyrus lies posterior. The atlas labels 4 and 3b help you compare its two banks.

Select each structure to light it on the atlas, then rotate until you can name what lies in front, behind and beneath it.

Targets

  • 4 · precentral
  • 3b · postcentral
  • 6d · dorsal premotor

Compare

Use the structure buttons to alternate between 4 and 3b. Rotate slightly toward the vertex and follow their shared central-region relationship; do not try to memorize the parcel outline.

Read the neighbours

  • The central region continues from the lateral gyri onto the medial paracentral lobule.
  • 6d provides premotor context anterior to the central region. These parcel labels subdivide cortex; they are not names for entire gyri.

Explain before revealing

A lesion approaches the central sulcus from anterior. Which cortical bank is encountered first, and how would your anatomical emphasis change for a lesion approaching from posterior?

Explanation

From anterior, the precentral bank (area 4) is met first, so the primary motor relationship leads the account. From posterior, the postcentral bank (area 3b) is met first and the somatosensory relationship leads. In either case, extend the account into the underlying white matter. The surface relationship helps frame the examination; it does not by itself predict the deficit.

In a surgical discussion

In a perirolandic discussion, describe both the cortical bank and the white matter beneath it. A gyrus name alone leaves the subcortical relationship unexplained.

Sources & anatomy notes

Evidence class: atlas

Precentral and postcentral parcels

HCP-MMP1 subdivides the central region into population reference labels, including primary motor, premotor, supplementary/cingulate and somatosensory territories. A parcel boundary does not define an individual functional boundary.

Evidence class: atlas · M1 · D1

What is actually installed

A group-average cortical surface with a population parcellation, a population-averaged bundle atlas, and gross subcortical meshes. No patient image, no registration, no functional map, no brainstem or thalamic nuclei.

Evidence class: atlas · D1 · D2 · D3

Teaching notes

Ask the learner to answer before opening the explanation. Compare the answer with the named structures and the cited method. Teaching point: From anterior, the precentral bank (area 4) is met first, so the primary motor relationship leads the account. From posterior, the postcentral bank (area 3b) is met first and the somatosensory relationship leads. In either case, extend the account into the underlying white matter. The surface relationship helps frame the examination; it does not by itself predict the deficit.

This relationship draws on 5 cited sources.

Relationship 2 of 10 · atlas

Continue onto the medial motor surface

Orient

The medial view brings the paracentral region and supplementary motor territory into the same frame. Compare posterior medial premotor parcel 6mp with the more anterior 6ma and area 4.

Select each structure to light it on the atlas, then rotate until you can name what lies in front, behind and beneath it.

Targets

  • 6mp · posterior medial premotor
  • 6ma · anterior medial premotor
  • SCEF · supplementary/cingulate
  • 4 · precentral

Compare

Compare 6mp, 6ma and 4 in the medial view, then inspect SCEF on the adjacent supplementary/cingulate territory. Say which way is anterior before describing the relationships.

Read the neighbours

  • 6mp and 6ma orient posterior and anterior medial premotor cortex. SCEF adds the adjacent supplementary/cingulate reference, so the medial-frontal account extends beyond two premotor parcels.
  • Movement initiation and movement execution are distinct clinical observations; a medial frontal deficit need not be explained by destruction of area 4.

Explain before revealing

Why can a medial frontal lesion impair movement even when the precentral cortex is preserved?

Explanation

Motor control includes medial premotor systems as well as primary motor cortex and descending pathways. A deficit of initiation is one possibility to consider. Its clinical characterization and time course must distinguish it from weakness caused by capsular, cortical or vascular injury.

In a surgical discussion

The cited medial frontal surgical series describes postoperative motor deficits after SMA-region resection. Use it to discuss an additional mechanism of impaired movement; recovery in that series is not an individual prognosis.

Sources & anatomy notes

Evidence class: atlas

Precentral and postcentral parcels

HCP-MMP1 subdivides the central region into population reference labels, including primary motor, premotor, supplementary/cingulate and somatosensory territories. A parcel boundary does not define an individual functional boundary.

Evidence class: atlas · M1 · D1

Teaching notes

Ask the learner to answer before opening the explanation. Compare the answer with the named structures and the cited method. Teaching point: Motor control includes medial premotor systems as well as primary motor cortex and descending pathways. A deficit of initiation is one possibility to consider. Its clinical characterization and time course must distinguish it from weakness caused by capsular, cortical or vascular injury.

This relationship draws on 4 cited sources.

Relationship 3 of 10 · reconstruction

Follow the fan into a descending corridor

Orient

The corticospinal reconstruction changes shape with depth: a broad supratentorial fan converges toward a narrower descending course. Follow that change before adding neighbouring systems.

Select each structure to light it on the atlas, then rotate until you can name what lies in front, behind and beneath it.

Targets

  • CST · corticospinal tract
  • 4 · precentral

Compare

Trace the displayed CST from its broad superior portion toward its narrow inferior portion. Rotate to an anterior view, then restore the lesson scene and compare the two projections.

Read the neighbours

  • Corona radiata describes the radiating white matter above the capsule; it is a region containing several fibre populations.
  • The displayed CST sample provides a course to inspect. Its visible endpoints are not proof that each line terminates in the highlighted parcel.

Explain before revealing

Why can two lesions beneath the same cortical region involve very different white matter relationships?

Explanation

The pathways fan out superiorly and converge with depth. Their neighbours and compactness therefore change along the course. Describe the level of the lesion as well as the overlying gyrus; the atlas supplies an orientation exercise, not a patient-specific lesion map.

In a surgical discussion

Depth changes the neighbourhood of a lesion: a superficial white matter relationship is different from a compact deep corridor. A lateral screenshot cannot substitute for evaluating the relationship in multiple planes.

Sources & anatomy notes

Evidence class: reconstruction

Corticospinal reference pathway

A descending reconstruction from a population atlas, sampled for display. Its side, family and source identify what is shown; its endpoints and line count do not identify an individual cortical origin, body part or axon count.

Evidence class: reconstruction · D2 · M4 · M11

Corona radiata and internal capsule

Projection pathways converge from the corona radiata toward the capsule. Use caudate or thalamus medially and the lentiform complex laterally to identify the level. The capsule is not segmented, and the displayed samples do not resolve its internal fibre ordering.

Evidence class: reconstruction · R2 · M5 · D2

Teaching notes

Ask the learner to answer before opening the explanation. Compare the answer with the named structures and the cited method. Teaching point: The pathways fan out superiorly and converge with depth. Their neighbours and compactness therefore change along the course. Describe the level of the lesion as well as the overlying gyrus; the atlas supplies an orientation exercise, not a patient-specific lesion map.

This relationship draws on 5 cited sources.

Relationship 4 of 10 · reconstruction

Motor-related origins extend beyond area 4

Orient

A descending system is not adequately described by a single cortical origin. Compare the primary motor, premotor and somatosensory reference parcels around the central region.

Select each structure to light it on the atlas, then rotate until you can name what lies in front, behind and beneath it.

Targets

  • 4 · precentral
  • 6d · dorsal premotor
  • 3b · postcentral

Compare

Alternate between 4, 6d and 3b. Keep the dim CST in view as a spatial reference, without treating every neighbouring parcel as a verified endpoint of this sample.

Read the neighbours

  • Usuda and colleagues reconstructed descending contributions from several motor-related and somatosensory regions in healthy volunteers.
  • Their tractography estimates describe one method and cohort; the displayed atlas does not separate those contributions into individual origin-specific bundles.

Explain before revealing

Does a postcentral origin make a descending streamline a primary motor-cortex fibre?

Explanation

No. Cortical origin, anatomical course and functional role are different descriptors. A pathway may descend from a somatosensory region without becoming an area-4 origin. This scene lets you compare labels, but does not classify its streamlines by origin.

In a surgical discussion

A proposed explanation of motor risk should consider premotor and postcentral relationships as well as area 4. Sparing one named parcel does not describe the full motor system.

Sources & anatomy notes

Evidence class: reconstruction

Corticospinal reference pathway

A descending reconstruction from a population atlas, sampled for display. Its side, family and source identify what is shown; its endpoints and line count do not identify an individual cortical origin, body part or axon count.

Evidence class: reconstruction · D2 · M4 · M11

Precentral and postcentral parcels

HCP-MMP1 subdivides the central region into population reference labels, including primary motor, premotor, supplementary/cingulate and somatosensory territories. A parcel boundary does not define an individual functional boundary.

Evidence class: atlas · M1 · D1

Teaching notes

Ask the learner to answer before opening the explanation. Compare the answer with the named structures and the cited method. Teaching point: No. Cortical origin, anatomical course and functional role are different descriptors. A pathway may descend from a somatosensory region without becoming an area-4 origin. This scene lets you compare labels, but does not classify its streamlines by origin.

This relationship draws on 5 cited sources.

Relationship 5 of 10 · atlas

Read the posterior limb by its neighbours

Orient

The posterior limb of the internal capsule lies between the thalamus medially and the lentiform nucleus laterally. The lentiform nucleus comprises putamen and globus pallidus.

Select each structure to light it on the atlas, then rotate until you can name what lies in front, behind and beneath it.

Targets

  • Thalamus (gross)
  • Putamen
  • Globus pallidus
  • CBT · corticobulbar tract

Compare

Find thalamus, putamen and pallidum around the descending sample. Use their relative positions to describe the corridor; the internal capsule itself is not a segmented mesh here.

Read the neighbours

  • Putamen is lateral to the pallidum; the capsular corridor is medial to the lentiform complex.
  • Discuss corticobulbar fibres at the genu and anterior posterior limb as a classical orientation, then contrast the more posterior localization reported by Yim. The ghosted CBT and frontopontine samples compare projection courses; they cannot resolve this difference or individual capsular fibre ordering.

Explain before revealing

On a sectional image, a white-matter interval has thalamus medially and pallidum laterally. Identify the capsular relationship and explain what would change in an anterior-limb section.

Explanation

This is the posterior-limb relationship. The lentiform complex remains lateral, while the medial neighbour in an anterior-limb section is caudate head. Use these grey-matter landmarks to establish the level before discussing the projection fibres within the interval.

In a surgical discussion

For a deep lesion, name the grey-matter structures on either side of the white matter relationship. This is more informative than describing a line as simply “near the basal ganglia.”

Sources & anatomy notes

Evidence class: atlas

Corona radiata and internal capsule

Projection pathways converge from the corona radiata toward the capsule. Use caudate or thalamus medially and the lentiform complex laterally to identify the level. The capsule is not segmented, and the displayed samples do not resolve its internal fibre ordering.

Evidence class: reconstruction · R2 · M5 · D2

Corticopontine families

The frontopontine sample supplies context near the descending CST. The broader corticopontine account rests partly on primate tracer work; those experiments do not verify each line or cortical origin of this human atlas sample.

Evidence class: experimental anatomy · M7 · D2

Deep grey around the capsule

Putamen, globus pallidus, caudate and thalamus at the coarsest scale of a group subcortical parcellation. Anterior and posterior thalamus are merged into one mesh; no nucleus is individually named or targetable here.

Evidence class: atlas · D3

Teaching notes

Ask the learner to answer before opening the explanation. Compare the answer with the named structures and the cited method. Teaching point: This is the posterior-limb relationship. The lentiform complex remains lateral, while the medial neighbour in an anterior-limb section is caudate head. Use these grey-matter landmarks to establish the level before discussing the projection fibres within the interval.

This relationship draws on 7 cited sources.

Relationship 6 of 10 · atlas

Distinguish anterior from posterior capsule

Orient

Moving anteriorly changes the medial neighbour of the capsule from thalamus toward caudate head. The lentiform complex remains lateral. This distinguishes two capsular relationships without relying on colour.

Select each structure to light it on the atlas, then rotate until you can name what lies in front, behind and beneath it.

Targets

  • Caudate nucleus
  • Thalamus (gross)
  • Putamen
  • Globus pallidus

Compare

Compare caudate and thalamus while keeping putamen and pallidum visible. Describe the anterior and posterior relationships aloud; do not call every interval the posterior limb.

Read the neighbours

  • The anterior limb is related to caudate head medially; the posterior limb is related to thalamus medially.
  • The genu is the bend between the limbs. This atlas does not segment that bend or its individual fibre subdivisions.

Explain before revealing

What changes on the medial side as you move from the anterior to the posterior capsular relationship?

Explanation

The reference changes from caudate head to thalamus. Keep putamen and pallidum as the lateral reference while changing the viewing angle. The exercise identifies neighbouring structures; it does not identify a safe passage between them.

In a surgical discussion

The clinical significance of a deep frontal trajectory depends on its position along the capsule, not just its distance from a basal-ganglia outline. Vascular relationships require additional anatomy beyond these meshes.

Sources & anatomy notes

Evidence class: atlas

Deep grey around the capsule

Putamen, globus pallidus, caudate and thalamus at the coarsest scale of a group subcortical parcellation. Anterior and posterior thalamus are merged into one mesh; no nucleus is individually named or targetable here.

Evidence class: atlas · D3

Teaching notes

Ask the learner to answer before opening the explanation. Compare the answer with the named structures and the cited method. Teaching point: The reference changes from caudate head to thalamus. Keep putamen and pallidum as the lateral reference while changing the viewing angle. The exercise identifies neighbouring structures; it does not identify a safe passage between them.

This relationship draws on 2 cited sources.

Relationship 7 of 10 · reconstruction

Add sensory pathways to the deep region

Orient

The thalamus is also a reference for sensory systems. Compare the medial lemniscus and superior thalamic radiation samples with the descending corticospinal course.

Select each structure to light it on the atlas, then rotate until you can name what lies in front, behind and beneath it.

Targets

  • ML · medial lemniscus
  • TR_S · superior thalamic radiation
  • Thalamus (gross)

Compare

Follow ML toward the thalamic region and TR_S toward the cortex. Separate the two named samples; the viewer does not join them across a measured synapse.

Read the neighbours

  • The displayed thalamus is a gross structure, not an atlas of individual relay nuclei.
  • Anatomical direction is knowledge brought to the image. Neither line colour nor a display sweep identifies afferent versus efferent signalling.

Explain before revealing

Can a continuous-looking ML–thalamus–cortex arrangement prove a single continuous axon?

Explanation

No. These are separate atlas objects. Spatial proximity does not establish a synapse, continuity or direction. Use the thalamus to orient the anatomical relay relationship while keeping its nuclei and the individual connections unresolved.

In a surgical discussion

When discussing a deep sensorimotor deficit, characterize sensation as well as strength. A motor-only bundle selection can hide a neighbouring sensory relationship.

Sources & anatomy notes

Evidence class: reconstruction

Ascending and thalamocortical families

Medial lemniscus and the anterior, superior and posterior thalamic radiations. The render encodes geometry only: it cannot show direction of conduction, so “ascending” is anatomy you bring to the picture.

Evidence class: reconstruction · M6 · D2

Thalamic relay territory

The installed Melbourne scale-1 thalamus is gross anatomy. It does not segment lateral geniculate, VMpo or other relay nuclei; no named nucleus can be inferred from the outline.

Evidence class: conceptual model · D3

Teaching notes

Ask the learner to answer before opening the explanation. Compare the answer with the named structures and the cited method. Teaching point: No. These are separate atlas objects. Spatial proximity does not establish a synapse, continuity or direction. Use the thalamus to orient the anatomical relay relationship while keeping its nuclei and the individual connections unresolved.

This relationship draws on 3 cited sources.

Relationship 8 of 10 · reconstruction

Distinguish cerebellar input and output routes

Orient

Motor coordination also involves cerebellar connections. Compare the middle and superior cerebellar peduncles with the dentatorubrothalamic sample and thalamic reference.

Select each structure to light it on the atlas, then rotate until you can name what lies in front, behind and beneath it.

Targets

  • SCP · superior cerebellar peduncle
  • MCP · middle cerebellar peduncle
  • DRTT · dentatorubrothalamic tract

Compare

Use the posterior view to identify the two peduncle samples, then follow DRTT toward the thalamic region. The dentate and red nuclei are not represented by meshes.

Read the neighbours

  • The middle cerebellar peduncle belongs to the pontocerebellar input route; the superior peduncle carries major cerebellar output pathways.
  • The DRTT sample illustrates a different relationship from the descending CST. Its name does not mean that all named nuclei have been rendered.

Explain before revealing

Which peduncle would you discuss when tracing a major cerebellar output route toward thalamus?

Explanation

The superior cerebellar peduncle. Contrast it with the middle peduncle in the pontocerebellar input route. These connections participate in a larger system; the separate atlas samples do not form a fully resolved circuit.

In a surgical discussion

The cited paediatric posterior-fossa cohort associated postoperative syndrome with proximal dentatothalamocortical pathway injury. Use that evidence to broaden the anatomical discussion beyond the CST, without predicting an individual outcome.

Sources & anatomy notes

Evidence class: reconstruction

Cortico-ponto-cerebello-thalamo-cortical loop

Middle and superior peduncle samples and the dentatorubrothalamic reconstruction orient parts of a larger system. The dentate, pontine and red nuclei are absent. A cited paediatric posterior-fossa association is not an individual prediction or proof of a continuous rendered circuit.

Evidence class: reconstruction · M8 · M7 · D2

Teaching notes

Ask the learner to answer before opening the explanation. Compare the answer with the named structures and the cited method. Teaching point: The superior cerebellar peduncle. Contrast it with the middle peduncle in the pontocerebellar input route. These connections participate in a larger system; the separate atlas samples do not form a fully resolved circuit.

This relationship draws on 3 cited sources.

Relationship 9 of 10 · functional measurement

Separate a motor map from a parcel map

Orient

Return to area 4. A cortical label helps orientation, but it does not divide this brain into measured hand, foot and mouth territories.

Select each structure to light it on the atlas, then rotate until you can name what lies in front, behind and beneath it.

Targets

  • 4 · precentral
  • 6mp · posterior medial premotor

Compare

Inspect area 4 and its medial continuation. Explain what an additional functional map would need to contribute; there is no hidden homunculus to reveal in the controls.

Read the neighbours

  • Gordon and colleagues found effector-related regions alternating with regions linked to action control using precision functional MRI.
  • That organization is a functional finding in other participants. The atlas contour supplies a different kind of boundary.

Explain before revealing

Would highlighting the upper part of parcel 4 establish the foot representation in an individual?

Explanation

No. It would establish which portion of a population parcel you chose to display. Identifying an individual functional territory needs an appropriate functional observation; its task and localization must accompany the claim.

In a surgical discussion

An anatomical hypothesis and an individual functional observation should remain separately identifiable when discussing a motor-area lesion. A familiar surface location does not make the missing measurement available.

Sources & anatomy notes

Evidence class: functional measurement

Effector and inter-effector territories

A functional organization measured with precision fMRI in other participants. It is discussed here and deliberately not painted onto the surface, because that measurement is not part of this dataset.

Evidence class: functional measurement · M2

Teaching notes

Ask the learner to answer before opening the explanation. Compare the answer with the named structures and the cited method. Teaching point: No. It would establish which portion of a population parcel you chose to display. Identifying an individual functional territory needs an appropriate functional observation; its task and localization must accompany the claim.

This relationship draws on 2 cited sources.

Relationship 10 of 10 · schematic

Explain a motor deficit at three levels

Orient

Build a short anatomical differential: cortical bank, deep projection corridor, and distributed motor control. Use a specific relationship for each explanation.

Select each structure to light it on the atlas, then rotate until you can name what lies in front, behind and beneath it.

Targets

  • 4 · precentral
  • 6mp · posterior medial premotor
  • Thalamus (gross)
  • Putamen

Compare

Compare the area-4 and medial-premotor references, then identify thalamus and putamen around CST. Use Restore lesson scene to return after inspecting a structure.

Read the neighbours

  • At the surface, distinguish primary motor from premotor and postcentral relationships.
  • At depth, describe capsular neighbours; for coordination or initiation, consider systems beyond a single descending bundle.

Explain before revealing

Give one reason a preserved area-4 outline cannot establish preservation of motor function.

Explanation

The outline says nothing about the state of the underlying descending pathways, adjacent blood supply or connected premotor systems. A useful account specifies the observed deficit and anatomical level, then checks the individual evidence rather than treating an atlas selection as a clinical finding.

In a surgical discussion

Teaching vignette: a resident attributes every postoperative movement problem to CST injury. Explain what the examination and individual imaging would need to distinguish before accepting that account.

Sources & anatomy notes

Evidence class: schematic

What is actually installed

A group-average cortical surface with a population parcellation, a population-averaged bundle atlas, and gross subcortical meshes. No patient image, no registration, no functional map, no brainstem or thalamic nuclei.

Evidence class: atlas · D1 · D2 · D3

Teaching notes

Ask the learner to answer before opening the explanation. Compare the answer with the named structures and the cited method. Teaching point: The outline says nothing about the state of the underlying descending pathways, adjacent blood supply or connected premotor systems. A useful account specifies the observed deficit and anatomical level, then checks the individual evidence rather than treating an atlas selection as a clinical finding.

This relationship draws on 7 cited sources.

Recap

How can you explain a motor deficit when the area-4 outline is preserved?

  1. Use the two banks of the central sulcus to establish the cortical relationship.
  2. Read the posterior capsular corridor between thalamus and the lentiform complex.
  3. Explain movement at cortical, projection-pathway and distributed-control levels.
Review the final explanation

The outline says nothing about the state of the underlying descending pathways, adjacent blood supply or connected premotor systems. A useful account specifies the observed deficit and anatomical level, then checks the individual evidence rather than treating an atlas selection as a clinical finding.

Full source list

  1. R1 · Frigeri et al., 2015 · microsurgical anatomy of the central lobe

    Human cadaveric dissections: precentral/postcentral gyri, paracentral lobule and vascular relationships. The atlas has no vascular layer.

    Evidence class: experimental anatomy

  2. M1 · Glasser et al., 2016 · multi-modal parcellation of human cerebral cortex

    HCP population reference built from converging cortical features. A parcel boundary here is a group boundary; it does not locate one person’s functional border and it has not been registered to any individual in this viewer.

    Evidence class: atlas

  3. D1 · Van Essen et al., 2013 · the WU-Minn Human Connectome Project overview

    Provenance for the S1200 group-average surface rendered here. A group-average midthickness surface is a population object; individual gyral and sulcal anatomy differs from it.

    Evidence class: atlas

  4. D2 · Yeh, 2022 · population-based tract-to-region connectome of the human brain

    Provenance for the HCP1065 population-averaged bundles rendered here. Every displayed line is an average-space reconstruction sampled for display; it is not a patient’s pathway and carries no direction of conduction.

    Evidence class: atlas

  5. D3 · Tian et al., 2020 · topographic organization of the human subcortex

    Provenance for the Melbourne Subcortex Atlas scale-1 meshes rendered here. Scale 1 is the coarsest level: anterior and posterior thalamus are merged and no brainstem nucleus is included.

    Evidence class: atlas

  6. M9 · Krainik et al., 2001 · supplementary motor area and motor deficit after medial frontal surgery

    Surgical series correlating resection extent with postoperative deficit and recovery. The recovery pattern belongs to that series and its follow-up, not to any picture on this screen.

    Evidence class: association

  7. M4 · Usuda et al., 2022 · corticospinal tracts arising from different cortical areas

    Healthy-volunteer tractography comparing descending contributions by cortical origin. Streamline distributions depend on acquisition, model and ROI recipe; they are not axon counts and they are not transferable to a patient.

    Evidence class: reconstruction

  8. R2 · Ribas et al., 2018 · microsurgical anatomy of the central core

    Stepwise human dissections of the insula, capsules, basal ganglia and thalamus. Gross atlas meshes illustrate only part of these layered relationships.

    Evidence class: experimental anatomy

  9. M11 · Maier-Hein et al., 2017 · the challenge of mapping the connectome with diffusion tractography

    Challenge dataset with a defined ground truth and many submitted pipelines. Its false-positive findings motivate caution; its error figures belong to that challenge and are not an error estimate for this atlas.

    Evidence class: reconstruction

  10. M5 · Holodny et al., 2005 · somatotopic organization of corticospinal tracts in the internal capsule

    Early DTI tractography of capsular organization, published explicitly against prior reports. A group ordering derived from one method is not a map you can transfer to an individual capsule.

    Evidence class: reconstruction

  11. R8 · Tredici et al., 1982 · restricted capsular lesions and motor localization

    CT and clinical observations of restricted internal-capsular lesions support classical motor localization while allowing individual variation. A lesion-based inference is not a resolved fibre map in this atlas.

    Evidence class: association

  12. R10 · Yim et al., 2013 · corticobulbar distribution in the internal capsule

    Capsular-infarct observations and a separate DTI sample placed corticobulbar relationships more posteriorly than classical genu accounts. Findings depend on level and method; this atlas cannot adjudicate the individual distribution.

    Evidence class: reconstruction

  13. M7 · Schmahmann & Pandya, 1997 · basilar pontine projections from prefrontal cortices

    Tracer experiments in rhesus monkey. Species and experimental scope limit translation; a monkey tracer result does not verify a human population reconstruction.

    Evidence class: experimental anatomy

  14. M6 · Behrens et al., 2003 · non-invasive mapping of thalamus–cortex connections

    Probabilistic diffusion tractography relating thalamic territory to cortical target. A connectivity-defined territory is a model output, not a nuclear boundary, and this viewer ships no thalamic nuclei.

    Evidence class: reconstruction

  15. M8 · Morris et al., 2009 · proximal dentatothalamocortical tract involvement in posterior fossa syndrome

    Clinical–imaging correlation in a paediatric posterior fossa cohort. An association between imaged tract involvement and a postoperative syndrome is not a prediction rule for an individual, and nothing in this scene measures it.

    Evidence class: association

  16. M2 · Gordon et al., 2023 · somato-cognitive action network in motor cortex

    Precision functional MRI and connectivity in a small set of deeply sampled participants. Effector and inter-effector observations are task, modality and population dependent, and none of that map is installed in this viewer.

    Evidence class: functional measurement